Comparative 18 F-FDG PET/CT and FAP-targeted PET/CT Findings in Parotid Warthin Tumor.
case_report · Level V
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- Record sourced from PubMed, PMID 41738886.
- Also identified by DOI 10.1097/RLU.0000000000006392.
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Abstract
Warthin tumor is the second most common benign parotid neoplasm and often shows marked uptake on 18 F-FDG PET/CT, frequently mimicking malignancy. In contrast, its imaging characteristics on fibroblast activation protein (FAP)-targeted PET/CT remain insufficiently defined. We report 2 cases of parotid Warthin tumors that demonstrated marked FDG uptake but absent or minimal uptake on FAP-targeted PET/CT using 68 Ga-FAPI-04 and 68 Ga-FAP-2286. This discordant imaging pattern suggests that FAP-targeted PET/CT may aid in distinguishing Warthin tumor from malignant lesions.
Medical subject headings
- Adenolymphoma
- Fibroblast Activation Protein Alpha
- Fluorodeoxyglucose F18
- Gelatinases
- Parotid Neoplasms
- Positron Emission Tomography Computed Tomography
- Serine Endopeptidases