Clinical Reasoning: A 49-Year-Old Man With Meningoencephalitis and Persistent Altered Mental Status.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 41771008.
- Also identified by DOI 10.1212/WNL.0000000000214777.
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Abstract
Persistent altered mental status in acute meningoencephalitis poses a significant diagnostic and therapeutic challenge. We report a 49-year-old man who presented with fever, headache, and status epilepticus. Despite initial positive bacterial cultures and appropriate antimicrobial therapy, his mentation remained poor. MRI brain suggested a likely diagnosis, which was subsequently confirmed on autopsy. This case highlights the importance of a systematic approach in evaluating persistent altered mental status in meningoencephalitis, incorporating a detailed clinical history, comprehensive systemic assessment, and timely, targeted investigations to explore a broad range of potential mechanisms.
Medical subject headings
- Meningoencephalitis
- Clinical Reasoning