FDG PET/CT in Duodenal Follicular Dendritic Cell Sarcoma.

Geng, Jian; Luo, Jie; Huang, Fang; Qian, Jianjun; Chu, Xiaoyuan · Clin Nucl Med · 2026

case_report · Level V

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Abstract

Follicular dendritic cell sarcoma (FDCS) of the duodenum is extremely rare. We describe the contrast-enhanced CT and FDG PET/CT findings in a case of duodenal FDCS. Contrast-enhanced CT revealed a large, irregular mass originating from the horizontal portion of the duodenum. The mass demonstrated heterogeneous enhancement, with internal areas of low-attenuation necrosis and coarse calcifications. The mass showed significantly increased FDG uptake. The patient underwent surgical resection, and histopathologic examination revealed a spindle cell tumor positive for CD21 and CD35, confirming the diagnosis of FDCS.

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