Optimizing elastic band resistance training for Metabolic Syndrome components in older adults: A systematic review, meta-analysis, and meta-regression of randomized controlled trials.

Saez-Berlanga, Angel; Gene-Morales, Javier; Babiloni-Lopez, Carlos; Jiménez-Martínez, Pablo; Juesas, Alvaro; Colado, Juan C · Arch Phys Med Rehabil · 2026

meta_analysis · Level I

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Abstract

To evaluate the effects of elastic band resistance training (EBRT) on metabolic syndrome (MetS) components in older adults and to explore associations between training parameters and body fat percentage using meta-regression, following PRISMA guidelines (PROSPERO CRD42023466027). Web of Science, PubMed (MEDLINE), EMBASE, EBSCO (SPORTDiscus; CINAHL), and SCOPUS were searched through September 2024. Randomized controlled trials comparing EBRT with non-active controls in physically independent, sedentary adults ≥65 years with MetS or at cardiometabolic risk. Risk of bias was assessed using the Cochrane tool and TesTex scale. Body composition, blood pressure, lipid profile, and fasting glucose were analyzed. Mean differences (MD) were pooled for outcomes reported in comparable units, whereas standardized mean differences (SMD) were used for body fat percentage and fat mass, with back-translation for interpretability. Meta-regressions explored study-level training covariates. Twenty-three trials (n=1134; age=70.4±4.5; 92.4% women) were included. EBRT reduced body fat percentage (SMD= -0.47 [-0.65 to -0.30], equivalent to -1.44 % [-2.00 to -0.92]), and fat mass (SMD= -0.28 [-0.54 to -0.02], equivalent to -1.57 kg [-3.08 to -0.11]). EBRT reduced total cholesterol (MD= -18.21 mg/dL [-29.82 to -6.61]), low-density lipoprotein (MD= -11.03 mg/dL [(-17.44 to -4.62]), triglycerides (MD= -11.98 mg/dL [-23.16 to -0.79]), fasting glucose (MD= -9.02 mg/dL [-15.48 to -2.56]), systolic (MD= -7.73 mmHg [-12.75 to -2.71]) and diastolic blood pressure (MD= -5.45 mmHg [(-7.92 to -2.99]), while increased high-density lipoprotein (MD= 2.42 mg/dL [0.42 to 4.43)]). Heterogeneity varied by outcome, with minimal publication bias. Meta-regression identified exploratory associations between greater fat reductions and program characteristics. EBRT is associated with clinically meaningful improvements in cardiometabolic risk factors in older adults at risk of MetS. Study-level associations with adiposity are exploratory and may inform future trials.