Mechanisms of action for digital therapeutics.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 41787047.
- Also identified by DOI 10.1038/s41746-026-02502-y and PMC identifier 13043777.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Digital therapeutics (DTx) are increasingly established, yet their mechanisms of action (MoA) remain underexplored. This article defines and categorizes DTx MoA through a novel conceptual framework, distinguishing them from conventional treatments. We specifically conceptualize therapeutic elements, cognitive-affective and behavioral changes, and segment the notion of "dose" into distinct categories. This actionable framework provides a systematic basis for enhancing DTx research, design, and clinical effectiveness.