Harnessing skull immunity for brain drug delivery.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 41795440.
- Also identified by DOI 10.1016/j.cell.2026.01.031.
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Abstract
Therapeutic delivery to the brain after stroke is limited by the blood-brain barrier. In this issue of Cell, Gao et al. bypass this obstacle by harnessing skull bone marrow immune cells to deliver drug-loaded nanoparticles to injured brain regions, improving outcomes and revealing a feasible translational strategy for targeted CNS therapy.
Medical subject headings
- Skull
- Brain
- Drug Delivery Systems