Clinical potential and challenges of spatially profiling tumor-infiltrating lymphocytes in early-stage breast cancer.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 41805747.
- Also identified by DOI 10.1371/journal.pmed.1004979 and PMC identifier 12974881.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Digitally automated spatial profiling of immune-tumor cell interactions using multispectral immunofluorescence holds promise as a biomarker to predict outcomes in early-stage breast cancer, but prospective validation and harmonization with existing biomarkers is necessary before clinical adoption.
Medical subject headings
- Breast Neoplasms
- Lymphocytes, Tumor-Infiltrating