Predicting steroid treatment benefit in IgA nephropathy: are we ready for precision care?

Abstract

The treatment of patients with IgA nephropathy at risk of disease progression often requires therapies addressing the underlying immunologic pathogenesis. To date, steroids remain a viable treatment option; however, their use should be balanced against known associated toxicity. Canney et al. developed a prediction tool that utilizes readily available clinical data to calculate the expected response to steroid therapy for an individual patient. This shift to data-informed, patient-specific decision is the essence of personalized care.