Old drug, new data: Broadening the therapeutic armamentarium for desmoid tumors.

Dossa, Fahima; Stacchiotti, Silvia; Gronchi, Alessandro · Clin Cancer Res · 2026

rct · Level II

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Abstract

Desmoid tumours are a locally invasive neoplasm that can exhibit unpredictable clinical behaviour. While treatment options are numerous, few are supported by level 1 evidence. A recent phase 3 trial evaluated the efficacy of long-used pegylated liposomal doxorubicin in patients with progressive desmoid tumours.