False Uptake of 18F-MFBG and 68Ga-DOTATATE in the Stellate Ganglion in a Pediatric Patient With Neuroblastoma.
case_report · Level V
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- Record sourced from PubMed, PMID 41894584.
- Also identified by DOI 10.1097/RLU.0000000000006408.
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Abstract
A 7-year-old girl with high-risk neuroblastoma was enrolled in a clinical trial. 18F-MFBG PET/CT revealed increased radiotracer accumulation anterior to the left first rib. A metastatic lesion could not be ruled out. Subsequent 68Ga-DOTATATE PET/CT also demonstrated abnormal tracer uptake in the same region. Additional imaging and clinical evaluation confirmed the finding to represent physiological uptake in the stellate ganglion. This case illustrates that false-positive uptake on both 18F-MFBG and 68Ga-DOTATATE PET/CT may occur in the stellate ganglion in pediatric patients and should therefore be considered in the differential diagnosis of focal tracer accumulation in the upper thoracic region.
Medical subject headings
- Organometallic Compounds
- Neuroblastoma
- Stellate Ganglion
- 3-Iodobenzylguanidine