The Effect of 222nm UVC Irradiation on Germ Density on Breast Implants and Epidermis.

Abstract

Bacterial colonization of breast implants can lead to infections and capsular contracture, making contamination prevention essential. While conventional UVC254 light is germicidal, it poses risks to human skin and eyes. In contrast, UVC222 effectively kills bacteria without harming mammalian cells due to limited stratum corneum penetration. This study investigates whether UVC222 irradiation can reduce bacterial density on breast implant shells and the epidermis of the submammary fold. This prospective, single-center study included 31 patients who underwent breast reduction surgery between August 1, 2023, and June 1, 2024. Finely microtextured implant shells (MESMO ®, POLYTECH Health and Aesthetics GmbH, Germany) were placed on the sterile, washed submammary fold prior to skin incision. The implant shells were either irradiated with UVC222 using a KrCl excimer lamp (STERILSYSTEMS GmbH, Austria) or left untreated. Additionally, full-thickness skin samples from the submammary fold were irradiated or used as controls. Microbiological analysis was performed on all samples. UVC222 exposure significantly reduced bacterial density and microbial diversity on both implant shells (p = 0.0009) and skin samples (p = 0.02), with coagulase-negative staphylococci species being the most prevalent microorganisms in both treated and untreated groups. This pilot study shows that UVC222 effectively reduces bacterial density on breast implant surfaces and submammary fold epidermis, supporting its potential as an intraoperative sterilization tool. Further studies are needed to assess long-term safety and efficacy in surgical settings.