18 F-FET PET/MRI in a Case of Gliosis Mimicking Tumor Recurrence After Surgery for Breast Cancer Brain Metastasis.

Lin, Shuyi; Gu, Bingxin; Li, Ye; Qi, Ming; Song, Shaoli · Clin Nucl Med · 2026

case_report · Level V

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Abstract

A 44-year-old woman, previously treated with surgery for breast cancer and a left frontal brain metastasis, presented with seizures. 18 F-FET PET/MRI demonstrated a 18 F-FET-avid, enhancing lesion at the prior brain surgical area, suggestive of recurrence. However, subsequent surgical pathology identified only gliosis, with no tumor. This case demonstrates a limitation of 18 F-FET PET/MRI in differentiating between benign and malignant intracranial lesions.

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