Cycling GLP-1 receptor agonist treatment induces therapeutic resistance and increased adiposity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 41915442.
- Also identified by DOI 10.1172/jci.insight.205174.
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Abstract
Stopping and restarting GLP-1 weight-loss drugs in mice made them less effective over time and increased fat gain compared with continuous treatment.
Medical subject headings
- Glucagon-Like Peptide-1 Receptor Agonists
- Adiposity
- Obesity