Complement inhibition: A whole new world.
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- Record sourced from PubMed, PMID 41922076.
- Also identified by DOI 10.3949/ccjm.93a.25076.
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Abstract
The complement system is a central component of the innate immune system, and it is a bridge to the adaptive immune system. With this broad functional reach, dysregulation of this system contributes to a wide range of inflammatory and autoimmune conditions. Drugs that inhibit the complement system have dramatically improved outcomes in many previously untreatable diseases, and the number of approved indications is growing rapidly, requiring specialists and generalists alike to be familiar with these drugs.
Medical subject headings
- Complement System Proteins
- Complement Inactivating Agents
- Autoimmune Diseases
- Complement Activation