Rebuilding the bridge: Functional AVN cells for cardiac repair.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 41932318.
- Also identified by DOI 10.1016/j.stem.2026.03.007.
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Abstract
Directing the differentiation of human pluripotent stem cells into atrioventricular node-like cells is a critical strategy for restoring atrioventricular node dysfunction in patients. In this issue, Lohbihler et al. define a BMP2-driven protocol to engineer functional conduction bridges that recapitulate the heart's native "gatekeeper" properties in vivo.
Medical subject headings
- Atrioventricular Node