Disparities of itch severity in outpatient clinics as measured by the ItchyQuant.

Chen, Rene F; Morrissette, Kali; Liu, Beiyu; Green, Cynthia L; Nicholas, Matilda W; Cole, Emily F; Chen, Suephy C · J Am Acad Dermatol · 2026

retrospective_cohort · Level III

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Abstract

ItchyQuant is a validated patient-reported outcome measure rating itch. Assessment of subjective itch is important in clinical care to adequately understand disease burden. To assess itch severity among patients seen at a high-volume academic dermatology center and characterize variations in itch severity by demographic group and primary diagnosis. ItchyQuant was sent to every patient via e-portal 7 days prior to any non-Mohs dermatology encounter. Multinomial logistic regression compared data collected over 2 years. Cohort included 8907 patients (mean age 52 years, 67.4% female, 75.0% White) who responded >0 to ItchyQuant. Increase in age, female sex, and Black race were significantly associated with a higher likelihood of both moderate and severe compared to mild itch. Hispanic compared to non-Hispanic patients were more likely to experience moderate itch. Patients with nonvisible sensations compared to inflammatory/rash diagnoses were more likely to report severe itch. Single-institution retrospective study; patient-reported outcome measures deployed only in English. Black, Asian, and Hispanic patients reported higher itch severities than White and non-Hispanic counterparts while overall itch severities were consistent across age groups >45 years. Our data highlight the feasibility of broad ItchyQuant deployment without clinical workflow disruptions and suggest that itch disparities exist.