Antibiotic resistance gene analyses in microbial communities: challenges and opportunities.

Larsson, D G Joakim; Flach, Carl-Fredrik; Kristiansson, Erik · Nat Commun · 2026

basic_science · Level V

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Abstract

Culture-independent antibiotic resistance gene analyses enable broad explorations of microbial communities but often fail to link such genes to bacterial hosts and genetic contexts. This makes assessing prevalence of resistant pathogens and likelihood of further transmission or resistance evolution uncertain.