68 Ga-DOTANOC PET/CT in a Case of Grade 1 Pancreatic NET With Renal Vein and Gonadal Vein Tumor Thrombus.

Dharmashaktu, Yamini; Damle, Nishikant A; Wakankar, Ritwik; Ganapathy, Chandrasekaran; Venugopal, Akhil · Clin Nucl Med · 2026

case_report · Level V

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Abstract

Pancreatic neuroendocrine tumors (PNETs) are uncommon neoplasms comprising approximately 1%-2% of all pancreatic malignancies. They display a wide clinical spectrum ranging from indolent, well-differentiated Grade 1 lesions to aggressive, poorly differentiated tumors. While metastatic spread to the liver is relatively common, vascular invasion and tumor thrombus formation are exceedingly rare in low-grade NETs. Here, we present an unusual postoperative case of a Grade 1 PNET with tumor recurrence, kidney infiltration, and tumor thrombus involving the left renal vein and extending into the gonadal vein.

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