Fibroblast Activation Targeted Imaging Identifies Coronary Restenosis.

Xi, Xiao-Ying; Yang, Shengwen; Tu, Bin; Zhao, Lin; Yang, Min-Fu · Clin Nucl Med · 2026

case_report · Level V

Where this comes from

Abstract

A 49-year-old woman with chronic total occlusion of the proximal left anterior descending (LAD) artery underwent a baseline 18 F-FAPI PET/CT, and showed no abnormal uptake in the coronary artery. New focal 18 F-FAPI activity appeared at the LAD stent ostium at 6 months and progressed by 1 year, preceding angiographically confirmed in-stent restenosis. This case demonstrates that 18 F-FAPI imaging may detect early fibro-inflammatory activity predictive of restenosis.

Medical subject headings