Development of Prostate Cancer Intramuscular Metastasis During 177 Lu-PSMA-617 Treatment.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 41949415.
- Also identified by DOI 10.1097/RLU.0000000000006420 and PMC identifier 13132040.
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Abstract
Intramuscular and subcutaneous tissue metastasis of prostate cancer is a rare and aggressive process. We describe the case of a 61-year-old man with metastatic castration-resistant prostate cancer who presented with growing left gluteal/proximal thigh masses during ongoing 177 Lu-PSMA-617 (Pluvicto) treatment. While post-Pluvicto imaging demonstrates markedly improved nodal and hepatic metastases, progressive development of multifocal left gluteal/proximal thigh intramuscular and subcutaneous tissue metastases suggests a heterogeneous treatment response to Pluvicto. This case shows rare soft tissue metastasis in a heterogeneous treatment response to Pluvicto.
Medical subject headings
- Prostatic Neoplasms
- Muscle Neoplasms
- Dipeptides
- Heterocyclic Compounds
- Heterocyclic Compounds, 1-Ring