Sympathetic NPY signaling at the crossroads of neuro-tumoral metabolism.
Where this comes from
- Record sourced from PubMed, PMID 41950901.
- Also identified by DOI 10.1016/j.cmet.2026.03.004.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Sympathetic neurons can co-release norepinephrine (NE) and neuropeptide Y (NPY). Contrary to its functions in the central nervous system, peripheral sympathetic NPY sustains energy expenditure and cellular proliferation. Here we discuss how tumors might co-opt this sympathetic influence to sustain their increased metabolism and proliferation.
Medical subject headings
- Neuropeptide Y
- Sympathetic Nervous System
- Neoplasms
- Receptors, Neuropeptide Y