Erectile dysfunction and antihypertensive therapy: A critical reappraisal.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 41963149.
- Also identified by DOI 10.1016/j.ejim.2026.106863.
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Abstract
Erectile dysfunction often coexists with arterial hypertension. They both share a common vascular pathophysiology, while antihypertensive treatment may also affect sexual function. Although some of the older antihypertensive drugs had a significant impact on erectile function, new antihypertensive drugs may exert a neutral or even beneficial effect. After scrutinized review, recent evidence paints a more nuanced picture. This article critically reviews the relationship between various classes of antihypertensive drugs and ED, discusses underlying mechanisms, and provides evidence-based recommendations tailored to clinical practice.
Medical subject headings
- Antihypertensive Agents
- Erectile Dysfunction
- Hypertension