Social Determinants of Health and Patient-Reported Outcome Measures Among Head and Neck Cancer Survivors.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 41978428.
- Also identified by DOI 10.1002/hed.70278.
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Abstract
To investigate the cumulative impact of individual- and neighborhood-level social determinants of health (SDoH) on patient-reported outcome measures (PROMs) among head and neck cancer (HNC) survivors. Among 93 survivors who underwent radiotherapy, associations between SDoH (independently and in a composite score) and validated PROMs were analyzed using univariable and multivariable regression models. For every 1-point increase in the composite SDoH score, indicating an increase in the number of adverse individual- and neighborhood-level factors, physical QoL decreased by 2.92 points (p = 0.010) and depression severity increased by 0.62 points (p = 0.018). Higher neighborhood deprivation and Medicaid/no insurance were associated with worse physical and social-emotional QoL, depression severity, and anxiety severity. Higher neighborhood deprivation was also associated with worse neck disability. Accumulating adverse individual- and neighborhood-level SDoH collectively increase the risk of poorer PROMs. Multilevel SDoH interventions are needed to improve health outcomes and promote equitable care in HNC.