Comparative Endophthalmitis Rates in Adult and Pediatric Patients Across Various Ophthalmic Procedures: An IRIS® Registry Analysis.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 41985695.
- Also identified by DOI 10.1016/j.ophtha.2026.04.011.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
To evaluate the incidence of endophthalmitis after ophthalmic surgery using a national ophthalmic registry. Retrospective clinical cohort study. Patients in the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight) who underwent ophthalmic surgeries were included in this analysis. Incidence of endophthalmitis during the first 30 days following surgery. Pediatric and adult patients in the IRIS Registry who were diagnosed with acute endophthalmitis within 30 days after surgery from 2016 to 2024. A total of 17,457,881 procedures were analyzed. Rates of endophthalmitis varied by procedure. Among adults, the highest incidence occurred following open globe repair (0.94%, 1 case per 106). The incidence of endophthalmitis was 0.097% (1 case per 1031) following vitrectomy for retinal detachment, 0.1% for trabeculectomy (1 case per 1000), 0.075% for tube shunts (1 case per 1333), 0.068% for scleral buckle surgery (1 case per 1459). The incidence following cataract surgery was 0.038% (1 case per 2652), 0.039% (1 case per 2551) following standalone MIGS, 0.02% (1 case per 5013) following goniotomy, and 0.011% for strabismus surgery (1 case per 9091). Among pediatric patients, the incidence of endophthalmitis following open globe repair was 0.87% (1 case per 115). The incidence of endophthalmitis was 0.415% (1 case per 675) following scleral buckle surgery, 0.11% (1 case per 871) following cataract surgery, 0.084% (1 case per 1190) following vitrectomy for retinal detachment, and 0.0072% (1 case per 13884) following strabismus surgery. The risk of endophthalmitis was significantly higher for pediatric versus adult patients following cataract surgery (P = 0.014). Endophthalmitis rates following same-date cataract and glaucoma surgery vs. glaucoma surgery alone did not significantly differ. There are variable rates of endophthalmitis following ophthalmic surgical procedures, with the highest incidence being open globe repair. MIGS procedures had comparable infection rates to standard cataract surgery. There was a higher rate of infection after cataract surgery in pediatric patients when compared with adults.