Taking the biology seriously makes models better.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 42003454.
- Also identified by DOI 10.7554/eLife.111070 and PMC identifier 13095206.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
A new biologically-informed training paradigm enables protein language models to predict affinity maturation trajectories for antibodies.
Medical subject headings
- Antibodies
- Antibody Affinity
- Models, Biological