18 F-FDG Uptake Outperforms 68 Ga-FAPI-04 in Papillary Renal Neoplasm With Reverse Polarity.

Lu, Yao; Li, Lin; Xiao, Liu · Clin Nucl Med · 2026

case_report · Level V

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Abstract

Papillary renal neoplasm with reverse polarity (PRNRP) is very rare. Herein, we report a case of imaging findings of PRNRP in a 75-year-old woman. On the 68 Ga-FAPI-04 PET/CT and 18 F-FDG PET/CT image, it presented as a soft-tissue nodule in the left renal pelvis with intense FDG uptake (SUVmax: 20.8) but no FAPI uptake. Postsurgical pathology supported a diagnosis of PRNRP.

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