Stevens-Johnson syndrome and toxic epidermal necrolysis in pregnancy.

Bouadi, Naïla; Ayoub, Aimina; Croitoru, David; Piguet, Vincent; Auger, Nathalie · Br J Dermatol · 2026

prospective_cohort · Level II

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Abstract

This longitudinal cohort study of 2.6 million pregnancies suggests that patients with a pre-pregnancy history of Stevens–Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are at risk of severe maternal morbidity at delivery. In contrast, patients who develop SJS/TEN during pregnancy are not at risk of severe maternal morbidity, but are at risk of preterm birth and caesarean delivery.