Memory difficulty and bone mineral density: The NHANES, 2013-2018.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 42023335.
- Also identified by DOI 10.4103/jfmpc.jfmpc_1183_25 and PMC identifier 13098833.
- Licence recorded as CC BY-NC-SA.
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Abstract
Whether memory difficulty is associated with bone mineral density (BMD) is still unclear. We examined the association between memory difficulty and BMD in US adults. This cross-sectional study identified 4383 individuals (2581 [58.9%] males). Memory difficulty data were collected during a face-to-face interview. Femoral neck, total hip, and lumbar spine BMD were measured by a Hologic QDR-4500A fan-beam dual-energy X-ray absorptiometry (DXA); BMD T-scores were calculated using the established method. The average age and body mass index for study participants were 39.5 years (SD = 13.4 years) and 28.6 kg/m<sup>2</sup> (SD = 6.6 kg/m<sup>2</sup>), respectively. In both unadjusted and adjusted models, memory difficulty was associated with decreased femoral neck and total hip BMD T-scores (all <i>P</i> < 0.05), but not with lumbar spine BMD T-scores. These associations were identical for males and females (all <i>P</i> interaction by sex >0.100). The negative association between memory difficulty and hip BMD appeared to be stronger in individuals <50 years old than in those ≥50 years old (<i>P</i> interaction <0.001). Memory difficulty was negatively associated with hip BMD, with stronger associations observed among individuals aged <50 years old.