Updated hepatitis D seroprevalence among HBsAg-positive persons aged ≥6 years in the United States, National Health and Nutrition Examination Survey, 2007‒2018.

Casillas, Shannon M; Chida, Asiya; Drobeniuc, Jan; Sandul, Amy L; Kamili, Saleem; Jiles, Ruth B; Thomas, David L; Tobian, Aaron A R et al. · Clin Infect Dis · 2026

cross_sectional · Level IV

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Abstract

To validate the accuracy of previously published US seroprevalence estimates for hepatitis D virus (HDV) antibody, we retested National Health and Nutrition Examination Survey samples from 2007‒2018 using a different assay. We found the HDV seroprevalence among hepatitis B surface antigen positive participants aged ≥6 years to be 1.26%.