The current and future landscape of AI foundation models for cancer management.

Niu, Chuang; Wang, Ge · Nat Commun · 2026

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Abstract

AI foundation models (FMs) are transforming cancer management and research. Here, we analyze the state-of-the-art FMs, discuss their impact on cancer management, and argue that the next generation of cancer AI FMs will be defined by multimodality, enhanced reasoning, maximized openness, and sustained human guidance.