A case of delayed detection of vertical transmission of HIV-1 due to maternal therapy with long-acting injectable cabotegravir plus rilpivirine.

Feiterna-Sperling, Cornelia; Albers, Eva; Rohr, Irena; Weizsäcker, Katharina; Menner, Nikolai; Bührer, Christoph; Corman, Victor Max; Obermeier, Martin et al. · Clin Infect Dis · 2026

case_report · Level V

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Abstract

We report on a 4-month-old infant with delayed HIV-1 diagnosis after maternal antiretroviral therapy with long-acting injectable cabotegravir plus rilpivirine (LA-CAB/RPV) in the third trimester. Prolonged viral suppression in HIV-infected infants exposed to maternal LA-CAB/RPV may necessitate molecular testing beyond three months of age to exclude infection.