Fatal transfusion-transmitted severe dengue in an immunocompromised host: case report and systematic literature review.

Tejo, Alexandre Mestre; Duarte-Neto, Amaro Nunes; Rena, Jacqueline Alves; Kruschewsky, Wdson Luis Lima; Romano, Camila Malta; de Souza, Caio Santos; Catozo, Raquel Gomes; Amorim, Mariene Ribeiro et al. · Clin Infect Dis · 2026

case_report · Level V

Where this comes from

Abstract

Transfusion-transmitted dengue remains a relevant risk during outbreaks. We report a transfusion-transmitted severe dengue case in a stem cell transplant recipient during the 2024 epidemic in Brazil, supported by phylogenetic linkage, evolving to a fatal outcome. This sentinel case highlights the potential severity of transfusion-transmitted dengue, particularly in immunocompromised hosts.