From hype to hope: reanimating phage therapy through evidence-based multidisciplinarity.
Where this comes from
- Record sourced from PubMed, PMID 42098130.
- Also identified by DOI 10.1038/s41467-026-72590-7 and PMC identifier 13153206.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Phage therapy must move beyond anecdote to clinical reproducibility. Despite compelling cases of bacteriophages curing otherwise untreatable infections, inconsistent outcomes and biological complexity continue to limit clinical adoption. Here we identify three foundational pillars-drug delivery, treatment effectiveness, and managing bacterial resistance that must be addressed through interdisciplinary collaboration to transform phage therapy from a niche intervention to a powerful weapon against antimicrobial resistance. The time for rigorous, translational phage science is now.
Medical subject headings
- Phage Therapy
- Bacteriophages
- Bacterial Infections