Clonal hematopoiesis in lung adenocarcinoma pathogenesis.

Parisi, Tiziana; Santibanez Ocampo, Blanca; Adelman, Jacob; Cai, Yuyan; McConkey, Marie; Gibson, Christopher J; Ebert, Benjamin L; Miller, Peter et al. · JCI Insight · 2026

basic_science · Level V

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Abstract

<article data-scroll-anchor="true" data-testid="conversation-turn-2" data-turn="assistant" data-turn-id="request-WEB:b9841efa-619a-4cf3-8708-cec126c071b3-0" dir="auto" tabindex="-1"> Age-related blood cell mutations (clonal hematopoiesis) reshape immune cells and lung tumor immune structures, but did not increase lung cancer growth in a genetically engineered mouse model. </article>.

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