Tracking time and space: A new integrative approach in spatiotemporal transcriptomics.

Zhong, Suijuan; Wu, Qian; Wang, Xiaoqun · Cell Stem Cell · 2026

basic_science · Level V

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Abstract

Niu et al.<sup>1</sup> introduce SPTEdU-seq, a strategy that integrates spatial transcriptomics with EdU-based temporal labeling to jointly capture transcriptional states and proliferative history. This approach provides a framework for resolving spatiotemporal cell dynamics in development, regeneration, and cancer.

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