CAR-A astrocytes for Alzheimer's: Promise and challenge.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 42102723.
- Also identified by DOI 10.1016/j.stem.2026.04.008.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
In a recent study in Science, Chen et al. engineer astrocytes with anti-amyloid chimeric antigen receptors (CARs) to enable sustained, antigen-directed clearance of amyloid-β (Aβ) in vivo, revealing how CAR design can shape both pathology and glial responses.
Medical subject headings
- Astrocytes
- Alzheimer Disease
- Receptors, Chimeric Antigen