The emerging role of digital dentistry in managing molar-incisor hypomineralization: A perspective.

Arias Guillén, Cinthya Jeanette; de Toledo Monteiro, Ulysses; Doalto, Anna Laura; Pereira Neto, João Sarmento; Puppin-Rontani, Regina Maria; Castilho, Aline · PLOS Digit Health · 2026

expert_opinion · Level V

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Abstract

Molar-incisor hypomineralization (MIH) remains one of the most challenging conditions in pediatric dentistry, with fragile enamel that compromises structural integrity, patient comfort, and the longevity of traditional restorative treatments. The unpredictable bonding to hypomineralized substrates results in frequent restoration failures, reinforcing the need for new approaches. In this opinion piece, we argue that digital dentistry offers promising strategies to improve precision, durability, and patient-centered care in MIH management. Drawing on a clinical case used as a proof of concept to illustrate feasibility, we describe a fully digital workflow including intraoral scanning, CAD/CAM design, and 3D-printed indirect restoration. Digital workflows may also enrich dental education by familiarizing students with emerging technologies. At the same time, we acknowledge key barriers such as cost, accessibility, and the clinician learning associated with digital adoption. Digital solutions hold promise as part of a broader strategy to improve care for patients with MIH.