Skin Problems in Search of Skin Solutions: A Wound Care Overview.

Kalogeromitros, Maria; Giannas, Emmanuel; Bellen Nordahl, Emma J; Pugliese, Francescantonio; Manning, Michael; Jones, Luke S; Chennupati, Vignesh; Gergoudis, Franklin R et al. · Ann Plast Surg · 2026

review · Level V

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Abstract

Effective wound healing depends on timely optimization of the wound environment and appropriate reconstructive strategy. Impaired healing, often driven by infection, ischemia, or systemic factors, increases the risk of chronic wounds and adverse scarring. This review highlights key principles of wound bed preparation, including assessment, debridement, infection control, and appropriate dressing selection. For wounds that fail to progress with standard care, advanced interventions such as skin grafting and cellular and tissue-based products play a critical role in promoting closure and improving outcomes. A structured, algorithmic approach to wound management is essential to optimize healing and minimize complications.