Recognizing and Addressing Treatable Traits in Patients With Chronic Rhinosinusitis With Nasal Polyposis: Can We Do Better?

Abstract

Despite a rising awareness of the treatable traits of chronic rhinosinusitis with nasal polyposis (CRSwNP), gaps in the recognition and management of these traits remain. The present article summarizes the findings of a scientific discussion involving an international panel of ENT (ear, nose, and throat) specialists, allergists, and pulmonologists, aiming to bridge different perspectives to promote collaborative care. The discussion highlights the complexity of CRSwNP and its multiple treatable traits, as well as the current challenges in assessing and treating these traits. The authors share clinical experience and best practices, underscoring the need for a standardized, evidence-based management approach centered around the individual patient's concerns and medical needs. They outline a management approach that extends beyond sinonasal disease, encompassing a wide spectrum of treatable traits, from common CRSwNP-associated comorbidities such as asthma and allergies, to systemic inflammation, environmental triggers, infections, pain, and behavioral and psychosocial factors. In addition, the article discusses methods to enhance both patient and physician understanding of treatable traits and their impact on disease severity and recurrence, ultimately aiming to improve clinical outcomes for those with CRSwNP.