Pearls & Oy-Sters: Plantar Agraphesthesia in Corticobasal Syndrome.
case_report · Level V
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- Record sourced from PubMed, PMID 42139639.
- Also identified by DOI 10.1212/WNL.0000000000218062 and PMC identifier 13182979.
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Abstract
We describe a 70-year-old man with no significant medical history who developed progressive left leg numbness, gait dysfunction, and recurrent falls. Within a year, he reported difficulty with both initiating steps and perceiving his left leg as his own. Neurologic evaluation revealed foot dystonia, bradykinesia, and plantar agraphesthesia. Electromyography and nerve conduction studies were unremarkable. Brain MRI demonstrated asymmetric parietal atrophy, greatest on the right. His symptoms did not improve with high-dose carbidopa-levodopa (900 mg/day). This case highlights plantar agraphesthesia as a valuable bedside sign of lower limb cortical sensory loss, even in the absence of hand involvement.
Medical subject headings
- Humans
- Male
- Aged
- Carbidopa
- Carbidopa/therapeutic use
- Magnetic Resonance Imaging
- Drug Combinations
- Levodopa