Mild 18 F-PSMA-1007 Uptake in a Giant Bone Island.

Xiao, Zhengguang; Chen, Ting; Dong, Aisheng; Nian, Shensheng; Bai, Yushu · Clin Nucl Med · 2026

case_report · Level V

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Abstract

A giant bone island, defined as having a diameter >2.0 cm, is rare. We describe 18 F-PSMA-1007 PET/CT findings in a patient with a giant bone island in the left femoral head. The giant bone island appeared as a well-defined sclerotic lesion measuring 2.2 cm in maximum diameter on CT and showed mild 18 F-PSMA-1007 uptake on PET. The increased PSMA uptake may suggest a possible PSMA expression related to osteoblastic activity.

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