Development of a protocol for intravenous infusion management in patients with aggressive behavior due to mental disorders: A Donabedian framework approach.

Liu, Liying; Sun, Yaling; Hao, Yujie; Zhang, Wanyu; Gao, Yan; Wei, Yulian; Wang, Lina; Wang, Honghui · PLoS One · 2026

expert_opinion · Level V

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Abstract

To establish a scientifically grounded and feasible intravenous infusion management protocol for patients with Aggressive behavior due to mental disorders. Guided by Donabedian's theory, an initial draft of the management protocol was developed through a comprehensive literature review and semi-structured interviews with clinical experts. From June to July 2024, two rounds of expert consultation were conducted, and revisions were made until the final protocol was established. The response rate for both rounds of expert questionnaires was 100%, with authority coefficients of 0.915 and 0.92. After the second round, the coefficients of variation for item importance ranged from 0 to 0.115 and from 0 to 0.107, while Kendall's W coefficients were 0.506 and 0.628, respectively, indicating statistically significant expert consensus (P < 0.05). Ultimately, the final protocol comprised 3 first-level items, 17 second-level items, and 41 third-level items. The intravenous infusion management protocol developed on the basis of Donabedian's theory is both rigorous and targeted, providing a foundation for the comprehensive management of intravenous infusion in patients with aggressive behavior.

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