UK National Screening Committee position statement on surrogate outcomes in cancer screening trials.

Batson, Sarah; Hackshaw, Allan; Mackie, Anne; Richards, Mike; Given-Wilson, Rosalind; Atakpa, Emma; Njagi, Edmund Njeru; Shinkins, Bethany et al. · BMJ · 2026

Level V

Where this comes from

Abstract

Surrogate outcomes may offer earlier evidence of benefit and initiate further evaluative work, but they cannot yet replace mortality as the definitive outcome in cancer screening trials, say <b>Sian Taylor-Phillips and colleagues</b>