Channeling teamwork: ATP and lipids cooperate to gate P2X receptors.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 42202033.
- Also identified by DOI 10.1126/sciadv.aei2053 and PMC identifier 13215215.
- Licence recorded as CC BY-NC.
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Abstract
P2X receptor structures resolved in a lipid environment reveal how subtype-specific ligand recognition, drug sensitivity, and channel gating are coupled.
Medical subject headings
- Adenosine Triphosphate
- Receptors, Purinergic P2X
- Ion Channel Gating
- Lipids