Considerations and best practices for respirometry.
review · Level V
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- Record sourced from PubMed, PMID 42229405.
- Also identified by DOI 10.1016/j.cmet.2026.05.001.
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Abstract
Oxygen consumption rate (OCR) measurements are now widely used to assess mitochondrial function and cellular metabolism. Here, we review the strengths and limitations of plate-based respirometry, propose unified reporting standards, and discuss how OCR measurements can be integrated with complementary assays to evaluate cellular energy demands and mitochondrial function.