Robotic-Assisted Extended Sistrunk Approach (RESA) for Salvage Surgery After Head and Neck Irradiation.

Wojtera, Bartosz; Beharry, Avinash; Lambercy, Karma; Dübi, Pascaline; Todic, Jelena; Simon, Christian · Head Neck · 2026

case_series · Level IV

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Abstract

The robotic-assisted extended "Sistrunk" approach (RESA) is a minimally invasive technique providing access to hypopharyngeal and laryngeal structures via a submental incision and vallecular pharyngotomy, bypassing the base of tongue. We report 10 RESA procedures in previously irradiated head and neck cancer patients, including six organ-preservation surgeries and four total laryngectomies. RESA enabled completion of the planned surgery, achieving R0 margins in all cases. Postoperative bleeding occurred in four patients (three Clavien-Dindo IIIb; one II). One cervical abscess was managed endoscopically. After total laryngectomy, three patients developed a subclinical pharyngeal dehiscence visualized on barium swallow exam, without evidence of a pharyngo-cutaneous fistula. Disease-specific survival was 100% (median 15.5 months); two patients died of unrelated causes. Swallowing improved or remained stable in seven patients at 1 year (three developed recurrence, a second primary, or died). RESA is a feasible salvage option with acceptable oncologic and functional outcomes in selected patients.