Connecting transcriptional control to RNA velocity and cell fate.
Where this comes from
- Record sourced from PubMed, PMID 42276033.
- Also identified by DOI 10.1016/j.cell.2026.05.029.
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Abstract
RNA velocity can predict the direction of cell-state change, but the regulatory programs shaping these changes remain difficult to identify. In this issue of Cell, Wang et al. introduce RegVelo, a framework that integrates gene regulatory networks into RNA velocity analysis to nominate candidate regulators that may bias cell fate.
Medical subject headings
- Transcription, Genetic
- RNA
- Gene Regulatory Networks