Placenta accreta spectrum in the 21st century: Challenging dogma and redefining disorder.

Jauniaux, Eric; Bartels, Helena C; Afshar, Yalda · PLoS Med · 2026

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Abstract

Placenta accreta spectrum (PAS) is a serious pregnancy complication caused by abnormal placental attachment to the uterus. In this Perspective, Eric Jauniaux and colleagues discuss emerging evidence that challenges our long-held pathophysiological understanding of PAS, and argue that a critical reassessment of definition, diagnosis, and management is overdue.

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