Multifocal Laryngotracheal Rosai-Dorfman Disease: 48-Month Remission After Surgical Resection.

Li, Ruoqi; Yan, Sunshun; Ni, Liyan; Xia, Siwen · Laryngoscope · 2026

case_report · Level V

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Abstract

A rare case of multifocal subglottic-tracheal Rosai-Dorfman disease (RDD) achieved sustained 48-month remission through surgical resection alone, without adjuvant therapy. This outcome suggests that surgery alone may serve as a viable alternative for select cases of multifocal airway RDD characterized by completely resectable lesions, no systemic involvement, and favorable anatomical accessibility.