Parathyroid Carcinoma Mimicking a Parathyroid Adenoma on [ 18 F]F-Choline-PET With Occult Metastases.
case_report · Level V
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- Record sourced from PubMed, PMID 42302384.
- Also identified by DOI 10.1097/RLU.0000000000006555 and PMC identifier 13317897.
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Abstract
An 80-year-old man with hypercalcemia and hyperparathyroidism was suspected of having a parathyroid adenoma, which was localized on [ 18 F]F-choline-PET/CT. Still, after surgical removal of the suspected adenoma with an intraoperative parathyroid hormone decrease of >50%, severe hypercalcemia recurred quickly. A repeated [ 18 F]F-choline-PET/CT raised suspicion of a single contralateral parathyroid adenoma or multiglandular disease. Given the inconclusive findings, a histological reassessment of the suspected parathyroid adenoma showed the presence of a singular vessel invasion, which alerted the diagnosis to parathyroid carcinoma. An additionally performed [ 18 F]FDG-PET/CT revealed a liver lesion and MRI confirmed multiple liver metastases, which could not be seen on [ 18 F]F-choline-PET/CT.
Medical subject headings
- Parathyroid Neoplasms
- Choline
- Adenoma
- Positron Emission Tomography Computed Tomography
- Positron-Emission Tomography